@inproceedings{bf714112ac474ab6acd741ce91a0c28e,
title = "Exploring the chemoresistance mechanisms of leukemia in a biomimetic 'leukemia-on-a-chip' microsystem",
abstract = "B-cell acute lymphoblastic leukemia (B-ALL) is the most common cancer among children. The survival rate of B-ALL patients has improved dramatically through chemotherapy, however, relapsed B-ALL remains a leading cause of cancer-related death in children. To address this, existing treatment strategies have exploited tumor-intrinsic survival mechanisms to develop targeted therapy, however, they do not account for the “leukemic bone marrow niche” that may maintain leukemia progression. Herein, we described a 3D biomimetic 'Leukemia-on-a-Chip' platform to investigate the critical leukemia-bone marrow interactions in regulating chemotherapy resistance.",
keywords = "Bone marrow, Chemoresistance, Leukemia-on-a-Chip, Microfluidics",
author = "Chao Ma and Weiqiang Chen",
note = "Publisher Copyright: Copyright{\textcopyright} (2018) by Chemical and Biological Microsystems Society.All rights reserved.; 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 ; Conference date: 11-11-2018 Through 15-11-2018",
year = "2018",
language = "English (US)",
series = "22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018",
publisher = "Chemical and Biological Microsystems Society",
pages = "152--153",
booktitle = "22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018",
}