Expression profile of Ldh-a in the developing rat Rattus norvegicus testis suggests regulation at the translational level

Kourosh Salehi-Ashtiani; Erwin Goldberg

doi:10.1016/0305-0491(94)00158-Q

Expression profile of Ldh-a in the developing rat Rattus norvegicus testis suggests regulation at the translational level

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Abstract

Expression of Ldh-a and Ldh-c mRNAs was examined in the rat testis. The mRNA levels of both Ldh-a and Ldh-c increase during testicular maturation. In the adult testis, Ldh-a mRNA is expressed maximally in primary spermatocytes. Comparison of the Ldh-a mRNA expression profile with its translation product suggests that this gene is translationally down-regulated during spermatogenesis.

Original language	English (US)
Pages (from-to)	623-627
Number of pages	5
Journal	Comparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume	110
Issue number	3
DOIs	https://doi.org/10.1016/0305-0491(94)00158-Q
State	Published - Mar 1995

Keywords

Gene expression
Isozyme switching
Lactate dehydrogenase
Ldh-c, Ldh-a
Puberty
Spermatogenesis
Translational regulation

ASJC Scopus subject areas

Biochemistry
Physiology
Molecular Biology

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10.1016/0305-0491(94)00158-Q

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title = "Expression profile of Ldh-a in the developing rat Rattus norvegicus testis suggests regulation at the translational level",

abstract = "Expression of Ldh-a and Ldh-c mRNAs was examined in the rat testis. The mRNA levels of both Ldh-a and Ldh-c increase during testicular maturation. In the adult testis, Ldh-a mRNA is expressed maximally in primary spermatocytes. Comparison of the Ldh-a mRNA expression profile with its translation product suggests that this gene is translationally down-regulated during spermatogenesis.",

keywords = "Gene expression, Isozyme switching, Lactate dehydrogenase, Ldh-c, Ldh-a, Puberty, Spermatogenesis, Translational regulation",

author = "Kourosh Salehi-Ashtiani and Erwin Goldberg",

year = "1995",

month = mar,

doi = "10.1016/0305-0491(94)00158-Q",

language = "English (US)",

volume = "110",

pages = "623--627",

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T1 - Expression profile of Ldh-a in the developing rat Rattus norvegicus testis suggests regulation at the translational level

AU - Salehi-Ashtiani, Kourosh

AU - Goldberg, Erwin

PY - 1995/3

Y1 - 1995/3

N2 - Expression of Ldh-a and Ldh-c mRNAs was examined in the rat testis. The mRNA levels of both Ldh-a and Ldh-c increase during testicular maturation. In the adult testis, Ldh-a mRNA is expressed maximally in primary spermatocytes. Comparison of the Ldh-a mRNA expression profile with its translation product suggests that this gene is translationally down-regulated during spermatogenesis.

AB - Expression of Ldh-a and Ldh-c mRNAs was examined in the rat testis. The mRNA levels of both Ldh-a and Ldh-c increase during testicular maturation. In the adult testis, Ldh-a mRNA is expressed maximally in primary spermatocytes. Comparison of the Ldh-a mRNA expression profile with its translation product suggests that this gene is translationally down-regulated during spermatogenesis.

KW - Gene expression

KW - Isozyme switching

KW - Lactate dehydrogenase

KW - Ldh-c, Ldh-a

KW - Puberty

KW - Spermatogenesis

KW - Translational regulation

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SN - 0305-0491

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EP - 627

JO - Comparative Biochemistry and Physiology -- Part B: Biochemistry and

JF - Comparative Biochemistry and Physiology -- Part B: Biochemistry and

IS - 3

ER -

Expression profile of Ldh-a in the developing rat Rattus norvegicus testis suggests regulation at the translational level

Abstract

Keywords

ASJC Scopus subject areas

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