@inbook{31a96a3fd9604f08b4595ce3472e4b57,
title = "Eye position-dependent opsoclonus in mild traumatic brain injury",
abstract = "Opsoclonus consists of bursts of involuntary, multidirectional, back-to-back saccades without an intersaccadic interval. We report a 60-year-old man with post-concussive headaches and disequilibrium who had small amplitude opsoclonus in left gaze, along with larger amplitude flutter during convergence. Examination was otherwise normal and brain MRI was unremarkable. Video-oculography demonstrated opsoclonus predominantly in left gaze and during pursuit in the left hemifield, which improved as post-concussive symptoms improved. Existing theories of opsoclonus mechanisms do not account for this eye position-dependence. We discuss theoretical mechanisms of this behavior, including possible dysfunction of frontal eye field and/or cerebellar vermis neurons; review ocular oscillations in traumatic brain injury; and consider the potential relationship between the larger amplitude flutter upon convergence and post-traumatic ocular oscillations.",
keywords = "Concussion, Eye position-dependence, Ocular flutter, Opsoclonus, Saccades, Fixation, Ocular/physiology, Ocular Motility Disorders/etiology, Humans, Middle Aged, Brain Concussion/complications, Male, Eye Movement Measurements, Saccades/physiology",
author = "Rizzo, {John Ross} and Hudson, {Todd E.} and Sequeira, {Alexandra J.} and Weiwei Dai and Yash Chaudhry and John Martone and Zee, {David S.} and Optican, {Lance M.} and Balcer, {Laura J.} and Galetta, {Steven L.} and Rucker, {Janet C.}",
note = "Publisher Copyright: {\textcopyright} 2019 Elsevier B.V.",
year = "2019",
doi = "10.1016/bs.pbr.2019.04.016",
language = "English (US)",
isbn = "9780444642547",
volume = "249",
series = "Progress in brain research",
publisher = "Elsevier B.V.",
pages = "65--78",
editor = "Stefano Ramat and Shaikh, {Aasef G.}",
booktitle = "Mathematical Modelling in Motor Neuroscience",
}