TY - GEN
T1 - Fast model-reference current injection using RT-Linux
AU - Butera, Robert J.
AU - Wilson, Christopher G.
AU - Rinzel, J.
AU - Smith, Jeffrey C.
PY - 1999
Y1 - 1999
N2 - The dynamic clamp, an electrophysiological experimental technique utilizing the real-time computation of simulated ion channel conductances interacting with an in vitro experiment, has recently become a popular approach in both neural and cardiac electrophysiology. This paper outlines a new software implementation of this technique, which allows for computation speeds significantly faster than previous approaches using commonplace computing hardware. Our approach uses open-source freely available software tools and is easily extensible. We also discuss implementation issues affecting performance that previously have not been discussed in the literature.
AB - The dynamic clamp, an electrophysiological experimental technique utilizing the real-time computation of simulated ion channel conductances interacting with an in vitro experiment, has recently become a popular approach in both neural and cardiac electrophysiology. This paper outlines a new software implementation of this technique, which allows for computation speeds significantly faster than previous approaches using commonplace computing hardware. Our approach uses open-source freely available software tools and is easily extensible. We also discuss implementation issues affecting performance that previously have not been discussed in the literature.
UR - http://www.scopus.com/inward/record.url?scp=0033323767&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033323767&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:0033323767
SN - 0780356756
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
BT - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PB - IEEE
T2 - Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
Y2 - 13 October 1999 through 16 October 1999
ER -