Fast tree search for enumeration of a lattice model of protein folding

Henry Cejtin; Jan Edler; Allan Gottlieb; Robert Helling; Hao Li; James Philbin; Neo Wingreen; Chao Tang

doi:10.1063/1.1423324

Fast tree search for enumeration of a lattice model of protein folding

Henry Cejtin, Jan Edler, Allan Gottlieb, Robert Helling, Hao Li, James Philbin, Neo Wingreen, Chao Tang

Computer Science

Research output: Contribution to journal › Article › peer-review

Abstract

A fast tree-search algorithm was used to find the ground states of all sequences for a 4X3X3 lattice HP model of proteins. The results confirm the existence of highly designable structures in a three-dimensional solvation model with a surface-to-core ratio of 2- to-1, close to the values for small natural proteins. Highly designable structures were found to differ geometrically from other structures.

Original language	English (US)
Pages (from-to)	352-359
Number of pages	8
Journal	Journal of Chemical Physics
Volume	116
Issue number	1
DOIs	https://doi.org/10.1063/1.1423324
State	Published - Jan 1 2002

ASJC Scopus subject areas

General Physics and Astronomy
Physical and Theoretical Chemistry

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10.1063/1.1423324

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AU - Edler, Jan

AU - Gottlieb, Allan

AU - Helling, Robert

AU - Li, Hao

AU - Philbin, James

AU - Wingreen, Neo

AU - Tang, Chao

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Fast tree search for enumeration of a lattice model of protein folding

Abstract

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