Feasibility and Acceptability of the Adherence Connection Counseling, Education, and Support (ACCESS) Proof of Concept: A Peer-Led, Mobile Health (mHealth) Cognitive Behavioral Antiretroviral Therapy (ART) Adherence Intervention for HIV-Infected (HIV+) Adolescents and Young Adults (AYA)

Ann Margaret Dunn Navarra; Michael G. Rosenberg; Maurade Gormley; Suzanne Bakken; Jason Fletcher; Robin Whittemore; Marya Gwadz; Charles Cleland; Gail D’Eramo Melkus

doi:10.1007/s10461-022-03913-0

Feasibility and Acceptability of the Adherence Connection Counseling, Education, and Support (ACCESS) Proof of Concept: A Peer-Led, Mobile Health (mHealth) Cognitive Behavioral Antiretroviral Therapy (ART) Adherence Intervention for HIV-Infected (HIV+) Adolescents and Young Adults (AYA)

Ann Margaret Dunn Navarra, Michael G. Rosenberg, Maurade Gormley, Suzanne Bakken, Jason Fletcher, Robin Whittemore, Marya Gwadz, Charles Cleland, Gail D’Eramo Melkus

Research output: Contribution to journal › Article › peer-review

Abstract

Effective antiretroviral therapy (ART) adherence strategies for HIV+ adolescents and young adults (AYA) are needed to prevent HIV-related morbidity, mortality, and onward transmission. In the Adherence Connection for Counseling, Education, and Support (ACCESS) pilot, an exploratory sequential mixed-methods design was used to develop and test a peer-led, mobile health (mHealth) cognitive behavioral ART adherence intervention. HIV+ AYA (ages 16–29 years) with unsuppressed plasma HIV RNA (HIV viral load) were eligible for this five-session intervention directed to improving ART adherence and HIV viral load. A total of 78 peer-led remote videoconferencing sessions (via WebEx) were delivered to 16 participants. High completion rates (97.5%) and client satisfaction scores (mean = 29.13 of 32; SD = 2.45) were observed. Self-reported ART adherence improved (32% increase in doses taken; 95th CI 11.2–53.3) with an annualized average rate of 47.5% (0.28 log₁₀) reduction in HIV viral load. We established proof of concept for the ACCESS peer-led, mHealth cognitive behavioral ART adherence intervention, with promising adherence and virologic outcome data.

Original language	English (US)
Pages (from-to)	1807-1823
Number of pages	17
Journal	AIDS and Behavior
Volume	27
Issue number	6
DOIs	https://doi.org/10.1007/s10461-022-03913-0
State	Published - Jun 2023

Keywords

Adherence
Behavioral interventions
Community health worker
HIV
Health disparities
Patient compliance
Peer support
Retention in care
Smartphone
Technology

ASJC Scopus subject areas

Social Psychology
Public Health, Environmental and Occupational Health
Infectious Diseases

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Navarra, A. M. D., Rosenberg, M. G., Gormley, M., Bakken, S., Fletcher, J., Whittemore, R., Gwadz, M., Cleland, C., & Melkus, G. DE. (2023). Feasibility and Acceptability of the Adherence Connection Counseling, Education, and Support (ACCESS) Proof of Concept: A Peer-Led, Mobile Health (mHealth) Cognitive Behavioral Antiretroviral Therapy (ART) Adherence Intervention for HIV-Infected (HIV+) Adolescents and Young Adults (AYA). AIDS and Behavior, 27(6), 1807-1823. https://doi.org/10.1007/s10461-022-03913-0

Feasibility and Acceptability of the Adherence Connection Counseling, Education, and Support (ACCESS) Proof of Concept: A Peer-Led, Mobile Health (mHealth) Cognitive Behavioral Antiretroviral Therapy (ART) Adherence Intervention for HIV-Infected (HIV+) Adolescents and Young Adults (AYA). / Navarra, Ann Margaret Dunn; Rosenberg, Michael G.; Gormley, Maurade et al.
In: AIDS and Behavior, Vol. 27, No. 6, 06.2023, p. 1807-1823.

Research output: Contribution to journal › Article › peer-review

Navarra, AMD, Rosenberg, MG, Gormley, M, Bakken, S, Fletcher, J, Whittemore, R, Gwadz, M, Cleland, C & Melkus, GDE 2023, 'Feasibility and Acceptability of the Adherence Connection Counseling, Education, and Support (ACCESS) Proof of Concept: A Peer-Led, Mobile Health (mHealth) Cognitive Behavioral Antiretroviral Therapy (ART) Adherence Intervention for HIV-Infected (HIV+) Adolescents and Young Adults (AYA)', AIDS and Behavior, vol. 27, no. 6, pp. 1807-1823. https://doi.org/10.1007/s10461-022-03913-0

Navarra AMD, Rosenberg MG, Gormley M, Bakken S, Fletcher J, Whittemore R et al. Feasibility and Acceptability of the Adherence Connection Counseling, Education, and Support (ACCESS) Proof of Concept: A Peer-Led, Mobile Health (mHealth) Cognitive Behavioral Antiretroviral Therapy (ART) Adherence Intervention for HIV-Infected (HIV+) Adolescents and Young Adults (AYA). AIDS and Behavior. 2023 Jun;27(6):1807-1823. doi: 10.1007/s10461-022-03913-0

Navarra, Ann Margaret Dunn ; Rosenberg, Michael G. ; Gormley, Maurade et al. / Feasibility and Acceptability of the Adherence Connection Counseling, Education, and Support (ACCESS) Proof of Concept : A Peer-Led, Mobile Health (mHealth) Cognitive Behavioral Antiretroviral Therapy (ART) Adherence Intervention for HIV-Infected (HIV+) Adolescents and Young Adults (AYA). In: AIDS and Behavior. 2023 ; Vol. 27, No. 6. pp. 1807-1823.

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abstract = "Effective antiretroviral therapy (ART) adherence strategies for HIV+ adolescents and young adults (AYA) are needed to prevent HIV-related morbidity, mortality, and onward transmission. In the Adherence Connection for Counseling, Education, and Support (ACCESS) pilot, an exploratory sequential mixed-methods design was used to develop and test a peer-led, mobile health (mHealth) cognitive behavioral ART adherence intervention. HIV+ AYA (ages 16–29 years) with unsuppressed plasma HIV RNA (HIV viral load) were eligible for this five-session intervention directed to improving ART adherence and HIV viral load. A total of 78 peer-led remote videoconferencing sessions (via WebEx) were delivered to 16 participants. High completion rates (97.5%) and client satisfaction scores (mean = 29.13 of 32; SD = 2.45) were observed. Self-reported ART adherence improved (32% increase in doses taken; 95th CI 11.2–53.3) with an annualized average rate of 47.5% (0.28 log10) reduction in HIV viral load. We established proof of concept for the ACCESS peer-led, mHealth cognitive behavioral ART adherence intervention, with promising adherence and virologic outcome data.",

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Feasibility and Acceptability of the Adherence Connection Counseling, Education, and Support (ACCESS) Proof of Concept: A Peer-Led, Mobile Health (mHealth) Cognitive Behavioral Antiretroviral Therapy (ART) Adherence Intervention for HIV-Infected (HIV+) Adolescents and Young Adults (AYA)

Abstract

Keywords

ASJC Scopus subject areas

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