Filamentous phage assembly: membrane insertion of the major coat protein.

P. Model, M. Russel, J. D. Boeke

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The assembly of filamentous bacteriophages has been studied in cells infected by wild-type and mutant phage; host mutants defective in bacteriophage assembly have also been isolated. Phage assembly takes place at the membrane, and requires insertion of the viral major coat protein. We present data on the physiology of this process and on the effects of amino acid sequence variations near to the coat protein amino terminus on membrane insertion, processing, and phage assembly.

    Original languageEnglish (US)
    Pages (from-to)389-400
    Number of pages12
    JournalProgress in clinical and biological research
    Volume64
    StatePublished - 1981

    ASJC Scopus subject areas

    • Medicine(all)

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