TY - GEN
T1 - FLUIDTIP FOR ADVANCED ATOMIC FORCE MICROSCOPY
AU - Glia, Ayoub
AU - Deliorman, Muhammedin
AU - Sukumar, Pavithra
AU - Qasaimeh, Mohammad A.
N1 - Publisher Copyright:
© 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.
PY - 2021
Y1 - 2021
N2 - Here, a polymeric atomic force microscopy (AFM) probe with embedded fluidic channels and apertures at the tip end (named FluidTIP) is developed for diverse applications of bio-patterning and single cell manipulations. The FluidTIP is fabricated using two-photon polymerization, and designed in complex three-dimensional (3D) geometries and with various features for seamless integration with experimental setups. In particular, its primary design included single fluidic channel and aperture for fluid injection or suction, while its advanced design included dual channels and apertures for simultaneous fluid injection and suction. In agreement with parametric characterization, the FluidTIP showed excellent capabilities for AFM imaging and force measurements along with attaining control over fluidic delivery and retrieval to/from the targeted biological microenvironment.
AB - Here, a polymeric atomic force microscopy (AFM) probe with embedded fluidic channels and apertures at the tip end (named FluidTIP) is developed for diverse applications of bio-patterning and single cell manipulations. The FluidTIP is fabricated using two-photon polymerization, and designed in complex three-dimensional (3D) geometries and with various features for seamless integration with experimental setups. In particular, its primary design included single fluidic channel and aperture for fluid injection or suction, while its advanced design included dual channels and apertures for simultaneous fluid injection and suction. In agreement with parametric characterization, the FluidTIP showed excellent capabilities for AFM imaging and force measurements along with attaining control over fluidic delivery and retrieval to/from the targeted biological microenvironment.
KW - 3D printing
KW - AFM
KW - Cell manipulation
KW - Force spectroscopy
KW - Microfluidics
KW - Single cell
UR - http://www.scopus.com/inward/record.url?scp=85136999694&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85136999694&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:85136999694
T3 - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 77
EP - 78
BT - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Microsystems Society
T2 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Y2 - 10 October 2021 through 14 October 2021
ER -