TY - GEN
T1 - Fluorescence molecular tomography of small animals using the radiative transfer equation for curved geometries
AU - Klose, Alexander D.
AU - Hielscher, Andreas H.
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2006
Y1 - 2006
N2 - We have developed a fluorescence image reconstruction algorithm for three-dimensional whole-body small animal imaging. Our method uses non-contact fluorescent light measurement data on the tissue surface of the animal and reconstructs the three-dimensional unknown luorophore concentration inside the tissue. The image reconstruction technique em-ploys a light propagation model based on the equation of radiative transfer, which is solved on a structured Cartesian grid by a finite-difference method. A blocking-off approach takes the curved tissue surface geometry of the animal into account. Our proposed method has the advantage that fast numerical solvers for the equation of radiative transfer can be used.
AB - We have developed a fluorescence image reconstruction algorithm for three-dimensional whole-body small animal imaging. Our method uses non-contact fluorescent light measurement data on the tissue surface of the animal and reconstructs the three-dimensional unknown luorophore concentration inside the tissue. The image reconstruction technique em-ploys a light propagation model based on the equation of radiative transfer, which is solved on a structured Cartesian grid by a finite-difference method. A blocking-off approach takes the curved tissue surface geometry of the animal into account. Our proposed method has the advantage that fast numerical solvers for the equation of radiative transfer can be used.
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U2 - 10.1364/bio.2006.tui14
DO - 10.1364/bio.2006.tui14
M3 - Conference contribution
AN - SCOPUS:85086493952
SN - 1557528071
SN - 9781557528070
T3 - Optics InfoBase Conference Papers
BT - Biomedical Topical Meeting, BIO 2006
PB - Optical Society of America (OSA)
T2 - Biomedical Topical Meeting, BIO 2006
Y2 - 19 March 2006 through 19 March 2006
ER -