Functional evolution of leptin of Ochotona curzoniae in adaptive thermogenesis driven by cold environmental stress

Agriculture & Biology

• Ochotona curzoniae 95%
• leptin 67%
• heat production 62%
• Ochotonidae 40%
• plateaus 12%
• cold stress 9%
• homeostasis 7%
• keystone species 6%
• resting metabolic rate 5%
• China 5%
• energy 5%
• energy expenditure 4%
• biogenesis 4%
• hypothalamus 4%
• hypoxia 4%
• food intake 4%
• acclimation 3%
• indigenous species 3%
• stress response 3%
• oxidation 3%
• mammals 3%
• hormones 3%
• mice 2%
• organisms 2%
• animals 1%
• temperature 1%
• testing 1%
• genes 1%
• proteins 1%
• methodology 1%

Medicine & Life Sciences

• Lagomorpha 98%
• Thermogenesis 71%
• Leptin 58%
• Cold Temperature 16%
• Homeostasis 6%
• Basal Metabolism 5%
• Organelle Biogenesis 5%
• Brown Adipose Tissue 5%
• Heat-Shock Proteins 4%
• Inbred C57BL Mouse 4%
• Hypothalamus 4%
• Energy Metabolism 4%
• Mammals 3%
• Hypoxia 3%
• Eating 3%
• Temperature 3%
• Hormones 3%
• Gene Expression 2%
• Animals 2%

Chemical Compounds

• Leptin 100%
• Thermogenic 7%
• Energy 6%
• Cope Reaction 5%
• Environment 5%
• Brown 4%
• Metabolic 3%
• Heat 3%
• Food 3%
• Protein 1%