Gastruloids Gain Muscle: Somite Formation in Embryo-Like Structures

Edwin A. Rosado-Olivieri; Ali H. Brivanlou

doi:10.1016/j.stem.2020.03.011

Gastruloids Gain Muscle: Somite Formation in Embryo-Like Structures

Edwin A. Rosado-Olivieri, Ali H. Brivanlou

Molecular Pathobiology

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Gastruloids are embryo-like structures that display key features of post-implantation embryonic development, yet whether they fully recapitulate in vivo embryogenesis remains unsolved. Recently in Nature, van den Brink et al. (2020) performed high-resolution gene expression analysis to identify significant similarities between mouse gastruloids and embryos in positional lineage segregation and somite formation.

Original language	English (US)
Pages (from-to)	467-468
Number of pages	2
Journal	Cell Stem Cell
Volume	26
Issue number	4
DOIs	https://doi.org/10.1016/j.stem.2020.03.011
State	Published - Apr 2 2020

ASJC Scopus subject areas

Molecular Medicine
Genetics
Cell Biology

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10.1016/j.stem.2020.03.011

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abstract = "Gastruloids are embryo-like structures that display key features of post-implantation embryonic development, yet whether they fully recapitulate in vivo embryogenesis remains unsolved. Recently in Nature, van den Brink et al. (2020) performed high-resolution gene expression analysis to identify significant similarities between mouse gastruloids and embryos in positional lineage segregation and somite formation.",

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Gastruloids Gain Muscle: Somite Formation in Embryo-Like Structures

Abstract

ASJC Scopus subject areas

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