Gastruloids Gain Muscle: Somite Formation in Embryo-Like Structures

Edwin A. Rosado-Olivieri, Ali H. Brivanlou

Research output: Contribution to journalComment/debatepeer-review


Gastruloids are embryo-like structures that display key features of post-implantation embryonic development, yet whether they fully recapitulate in vivo embryogenesis remains unsolved. Recently in Nature, van den Brink et al. (2020) performed high-resolution gene expression analysis to identify significant similarities between mouse gastruloids and embryos in positional lineage segregation and somite formation.

Original languageEnglish (US)
Pages (from-to)467-468
Number of pages2
JournalCell Stem Cell
Issue number4
StatePublished - Apr 2 2020

ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Cell Biology


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