Generalized vibrotactile allodynia in a patient with temporomandibular disorder

Roger B. Fillingim, Lori A. Fillingim, Mark Hollins, Asgeir Sigurdsson, William Maixner

Research output: Contribution to journalArticlepeer-review


This report presents the findings from a psychophysical study of vibrotactile responses in a patient diagnosed with temporomandibular disorder (TMD). This patient unexpectedly reported pain due to innocuous vibrotactile stimulation, and this allodynia appeared to have a component of temporal summation. The pain response occurred not only in the region of the clinical pain (the face), but also on the volar forearm, where the patient reported no clinical pain. Administration of the N-methyl-D-aspartate (NMDA) receptor antagonist dextromethorphan (DM), but not vehicle, attenuated the vibration-induced pain at both sites. Copyright (C) 1998 International Association for the Study of Pain. Published by Elsevier Science B.V.

Original languageEnglish (US)
Pages (from-to)75-78
Number of pages4
Issue number1
StatePublished - Oct 1998


  • Allodynia
  • Dextromethorphan
  • N-methyl-D-aspartate antagonist
  • Temporomandibular disorder
  • Vibrotactile perception

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Anesthesiology and Pain Medicine


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