Genetic network during neural crest induction: From cell specification to cell survival

Ben Steventon, Carlos Carmona-Fontaine, Roberto Mayor

Research output: Contribution to journalReview articlepeer-review

Abstract

The concerted action of extracellular signals such as BMP, Wnt, FGF, RA and Notch activate a genetic program required to transform a naïve ectodermal cell into a neural crest cell. In this review we will analyze the extracellular signals and the network of transcription factors that are required for this transformation. We will propose the division of this complex network of factors in two main steps: an initial cell specification step followed by a maintenance or cell survival step.

Original languageEnglish (US)
Pages (from-to)647-654
Number of pages8
JournalSeminars in Cell and Developmental Biology
Volume16
Issue number6
DOIs
StatePublished - Dec 2005

Keywords

  • BMP
  • Cell survival
  • FGF
  • Genetic cascade
  • Neural crest
  • Retinoic acid
  • Wnt

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology

Fingerprint Dive into the research topics of 'Genetic network during neural crest induction: From cell specification to cell survival'. Together they form a unique fingerprint.

Cite this