TY - JOUR
T1 - Global estimate of the prevalence of post-Traumatic stress disorder among adults living with HIV
T2 - A systematic review and meta-Analysis
AU - Tang, Chulei
AU - Goldsamt, Lloyd
AU - Meng, Jingjing
AU - Xiao, Xueling
AU - Zhang, Li
AU - Williams, Ann Bartley
AU - Wang, Honghong
N1 - Funding Information:
CT is supported by the Scholarship from China Scholarship Council (CSC.201806370166).
Publisher Copyright:
© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
PY - 2020/4/27
Y1 - 2020/4/27
N2 - OBJECTIVES: Although people living with HIV (PLWH) have been disproportionately affected by post-traumatic stress disorder (PTSD), the global prevalence of PTSD among PLWH is unknown. This study aimed to systematically review the prevalence of PTSD among PLWH worldwide and explore variation in prevalence across sociodemographic and methodological factors.DESIGN: A meta-analysis using a random-effects model was conducted to pool the prevalence estimated from individual studies, and subgroup analyses were used to analyse heterogeneities.SETTING, PARTICIPANTS AND MEASURES: Observational studies providing PTSD prevalence data in an adult HIV population were searched from January 2000 to November 2019. Measurements were not restricted, although the definition of PTSD had to align with the Diagnostic and Statistical Manual of Mental Disorders or the International Classification of Diseases diagnostic criteria.RESULTS: A total of 38 articles were included among 2406 records identified initially. The estimated global prevalence of PTSD in PLWH was 28% (95% CI 24% to 33%). Significant heterogeneity was detected in the proportion of PLWH who reported PTSD across studies, which was partially explained by geographic area, population group, measurement and sampling method (p<0.05).CONCLUSION: PTSD among PLWH is common worldwide. This review highlights that PTSD should be routinely screened for and that more effective prevention strategies and treatment packages targeting PTSD are needed in PLWH.
AB - OBJECTIVES: Although people living with HIV (PLWH) have been disproportionately affected by post-traumatic stress disorder (PTSD), the global prevalence of PTSD among PLWH is unknown. This study aimed to systematically review the prevalence of PTSD among PLWH worldwide and explore variation in prevalence across sociodemographic and methodological factors.DESIGN: A meta-analysis using a random-effects model was conducted to pool the prevalence estimated from individual studies, and subgroup analyses were used to analyse heterogeneities.SETTING, PARTICIPANTS AND MEASURES: Observational studies providing PTSD prevalence data in an adult HIV population were searched from January 2000 to November 2019. Measurements were not restricted, although the definition of PTSD had to align with the Diagnostic and Statistical Manual of Mental Disorders or the International Classification of Diseases diagnostic criteria.RESULTS: A total of 38 articles were included among 2406 records identified initially. The estimated global prevalence of PTSD in PLWH was 28% (95% CI 24% to 33%). Significant heterogeneity was detected in the proportion of PLWH who reported PTSD across studies, which was partially explained by geographic area, population group, measurement and sampling method (p<0.05).CONCLUSION: PTSD among PLWH is common worldwide. This review highlights that PTSD should be routinely screened for and that more effective prevention strategies and treatment packages targeting PTSD are needed in PLWH.
KW - HIV/AIDS
KW - meta-Analysis
KW - post-Traumatic stress disorder
KW - prevalence
KW - Prevalence
KW - Observational Studies as Topic/statistics & numerical data
KW - Humans
KW - Stress Disorders, Post-Traumatic/epidemiology
KW - Self Report/statistics & numerical data
KW - Publication Bias
KW - Adult
KW - Acquired Immunodeficiency Syndrome/epidemiology
KW - HIV Infections/epidemiology
KW - Global Health/statistics & numerical data
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U2 - 10.1136/bmjopen-2019-032435
DO - 10.1136/bmjopen-2019-032435
M3 - Article
C2 - 32345695
AN - SCOPUS:85084170033
SN - 2044-6055
VL - 10
JO - BMJ open
JF - BMJ open
IS - 4
M1 - e032435
ER -