Global nucleosome distribution and the regulation of transcription in yeast

Sevinc Ercan, Michael J. Carrozza, Jerry L. Workman

Research output: Contribution to journalShort survey

Abstract

Recent studies show that active regulatory regions of the yeast genome have a lower density of nucleosomes than other regions, and that there is an inverse correlation between nucleosome density and the transcription rate of a gene. This may be the result of transcription factors displacing nucleosomes.

Original languageEnglish (US)
Article number243
JournalGenome biology
Volume5
Issue number10
DOIs
StatePublished - 2004

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Cell Biology

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