Glycogen concentration and DNA synthesis in isoproterenol-stimulated salivary glands

D. Malamud, R. Baserga

Research output: Contribution to journalArticlepeer-review

Abstract

Following injection of IPR there is an initial decrease and then a marked increase in concentration of salivary gland glycogen correlated with an increased incorporation of 14C-glucose into glycogen. Several experiments have indicated that there is a close relationship between elevated glycogen levels and subsequent DNA synthesis, since any induced decrease in peak glycogen concentration results in a decreased incorporation of 3HTdR into DNA. Furthermore, after a second injection of IPR, DNA synthesis is depressed until high levels of glycogen are restored.

Original languageEnglish (US)
Pages (from-to)581-588
Number of pages8
JournalExperimental Cell Research
Volume50
Issue number3
DOIs
StatePublished - Jun 1968

ASJC Scopus subject areas

  • Cell Biology

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