Glycophorins, Blood Groups, and Protection from Severe Malaria

Samuel C. Wassmer, Jane M. Carlton

Research output: Contribution to journalShort surveypeer-review

Abstract

In Malaŵi, Malungo alibe odi is a saying that translates as: 'Malaria does not ask permission before coming in'. The recent finding of a new severe malaria resistance locus next to a cluster of glycophorin genes involved in Plasmodium falciparum erythrocyte invasion seems to suggest otherwise: that evolutionary pressure is enabling erythrocytes to lock the door to keep malaria out.

Original languageEnglish (US)
Pages (from-to)5-7
Number of pages3
JournalTrends in Parasitology
Volume32
Issue number1
DOIs
StatePublished - Jan 1 2016

Keywords

  • Genome-wide association study
  • Plasmodium falciparum malaria

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

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