Health and economic impact of the seasonal influenza vaccination programme in England

Marc Baguelin; Mark Jit; Elizabeth Miller; William John Edmunds

doi:10.1016/j.vaccine.2012.03.019

Health and economic impact of the seasonal influenza vaccination programme in England

Marc Baguelin, Mark Jit, Elizabeth Miller, William John Edmunds

Global Public Health

Research output: Contribution to journal › Article › peer-review

Abstract

Background: The seasonal influenza vaccination programme in England targets individuals over 65. years old and in clinical risk groups. Methods: A model of influenza transmission and disease was fitted to weekly primary care consultations due to influenza in a typical pre-pandemic season (2006/2007). Different scenarios were constructed about influenza severity and how well vaccines match circulating strains to assess the impact and cost-effectiveness of the current vaccination programme. Results: A well-matched vaccine may reduce the incidence of laboratory-confirmed influenza illness from 8.2% (95% range 4.3-13%) to 5.9% (95% range 2.9-9.7%), with 56-73% of this due to indirect protection. The programme is likely to be cost-effective unless both low severity and poor matching is assumed. Conclusion: The current seasonal influenza vaccination programme appears to substantially reduce disease burden and provides good value for money.

Original language	English (US)
Pages (from-to)	3459-3462
Number of pages	4
Journal	Vaccine
Volume	30
Issue number	23
DOIs	https://doi.org/10.1016/j.vaccine.2012.03.019
State	Published - May 14 2012

Keywords

Cost-effectiveness
Influenza
Vaccine

ASJC Scopus subject areas

Molecular Medicine
General Immunology and Microbiology
General Veterinary
Public Health, Environmental and Occupational Health
Infectious Diseases

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10.1016/j.vaccine.2012.03.019

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AU - Edmunds, William John

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Health and economic impact of the seasonal influenza vaccination programme in England

Abstract

Keywords

ASJC Scopus subject areas

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