High osmotic pressure chromatography of poly(ε-caprolactone) in near-Θ solvent

Dean Lee, Yingchuan Gong, Iwao Teraoka

Research output: Contribution to journalArticlepeer-review


High osmotic pressure chromatography (HOPC) was applied to preparative separation of poly(ε-caprolactone), a biodegradable polymer, by molecular weight (MW). When the solvent was toluene, a near-Θ solvent for the polymer, the MW distribution was narrow in all of the separated fractions except late fractions. In dioxane, which is a good solvent, in contrast, the MW distribution narrowed only in early fractions. The difference is explained by a recent computer simulation study on partitioning in Θ solvent and a concept of self-adjusting pore size by adsorbed polymer.

Original languageEnglish (US)
Pages (from-to)7093-7099
Number of pages7
Issue number18
StatePublished - Aug 27 2002

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Inorganic Chemistry
  • Materials Chemistry


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