Abstract
Theory is Developed for frequency shift and linewidth-broadening induced by rodlike bacteria bound to micro-optical resonators. Optical shift of whispering gallery modes (WGMs) is modeled by introducing a form factor that accounts for random horizontal orientation of cylindrical bacteria bound by their high refractive index cell walls. Linewidth-broadening is estimated from scattering losses. Analytic results are confirmed by measurement using E.Coli as model system (∼102 bacteria/mm2 sensitivity), establishing the WGM biosensor as sensitive technique for detection and analysis of micro-organisms.
Original language | English (US) |
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Pages (from-to) | 17410-17423 |
Number of pages | 14 |
Journal | Optics Express |
Volume | 15 |
Issue number | 25 |
DOIs | |
State | Published - Dec 12 2007 |
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics