@inproceedings{9ba7902564d44945b2846ec4acb9c2b5,
title = "High-throughput proteomic sample preconcentration in pdms microfluidic chip using surface-patterned ion-selective membrane",
abstract = "We report a novel method of fabricating a high-throughput protein preconcentrator in PDMS microfluidic chip format. Using microstamping or microflow patterning of ion-selective resin, we can build a submicron thick ion-selective membrane on the glass substrate. By simply plasma bonding a PDMS device on top of the thin membrane, we can rapidly prototype a PDMS preconcentrator without complicated microfabrication processes. The PDMS preconcentrator shows a highly efficient preconcentration with a factor as high as ~104 in 5 min. Our fabrication method even allows building a massively parallel array of preconcentrators to increase the concentrated sample volume, which facilitates the integration of preconcentrator into various detectors.",
keywords = "Ion-selective membrane, Microcontact printing, Preconcentration, Protein",
author = "Lee, {Jeong Hoon} and Song, {Yong Ak} and Kim, {Sung Jae} and Jongyoon Han",
note = "Publisher Copyright: {\textcopyright} 2007 CBMS.; 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 ; Conference date: 07-10-2007 Through 11-10-2007",
year = "2007",
language = "English (US)",
series = "Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007",
publisher = "Chemical and Biological Microsystems Society",
pages = "1198--1200",
editor = "Jean-Louis Viovy and Patrick Tabeling and Stephanie Descroix and Laurent Malaquin",
booktitle = "Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007",
}