TY - JOUR
T1 - Higher Stress in Oncology Patients is Associated With Cognitive and Evening Physical Fatigue Severity
AU - Morse, Lisa
AU - Paul, Steven M.
AU - Cooper, Bruce A.
AU - Oppegaard, Kate
AU - Shin, Joosun
AU - Calvo-Schimmel, Alejandra
AU - Harris, Carolyn
AU - Hammer, Marilyn
AU - Conley, Yvette
AU - Wright, Fay
AU - Levine, Jon D.
AU - Kober, Kord M.
AU - Miaskowski, Christine
N1 - Publisher Copyright:
© 2022 American Academy of Hospice and Palliative Medicine
PY - 2023/3
Y1 - 2023/3
N2 - Context: Cognitive and physical fatigue are common symptoms experienced by oncology patients. Exposure to stressful life events (SLE), cancer-related stressors, coping styles, and levels of resilience may influence the severity of both dimensions of fatigue. Objectives: Evaluate for differences in global, cancer-specific, and cumulative life stress, as well as resilience and coping in oncology patients (n=1332) with distinct cognitive fatigue AND evening physical fatigue profiles. Methods: Latent profile analysis, which combined the two symptom scores, identified three subgroups of patients with distinct cognitive fatigue AND evening physical fatigue profiles (i.e., Low, Moderate, High). Patients completed measures of global, cancer-specific, and cumulative life stress as well measures of resilience and coping. Differences among the latent classes in the various measures were evaluated using parametric and nonparametric tests. Results: Compared to Low class, the other two classes reported higher global and cancer-specific stress. In addition, they reported higher occurrence rates for sexual harassment and being forced to touch prior to 16 years of age. Compared to the other two classes, High class reported lower resilience scores and higher use of denial, substance use, and behavioral disengagement. Conclusion: To decrease both cognitive and evening physical fatigue, clinicians need to assess for relevant stressors and initiate interventions to increase resilience and the use of engagement coping strategies. Additional research is warranted on the relative contribution of various social determinants of health to both cognitive and physical fatigue in oncology patients receiving chemotherapy.
AB - Context: Cognitive and physical fatigue are common symptoms experienced by oncology patients. Exposure to stressful life events (SLE), cancer-related stressors, coping styles, and levels of resilience may influence the severity of both dimensions of fatigue. Objectives: Evaluate for differences in global, cancer-specific, and cumulative life stress, as well as resilience and coping in oncology patients (n=1332) with distinct cognitive fatigue AND evening physical fatigue profiles. Methods: Latent profile analysis, which combined the two symptom scores, identified three subgroups of patients with distinct cognitive fatigue AND evening physical fatigue profiles (i.e., Low, Moderate, High). Patients completed measures of global, cancer-specific, and cumulative life stress as well measures of resilience and coping. Differences among the latent classes in the various measures were evaluated using parametric and nonparametric tests. Results: Compared to Low class, the other two classes reported higher global and cancer-specific stress. In addition, they reported higher occurrence rates for sexual harassment and being forced to touch prior to 16 years of age. Compared to the other two classes, High class reported lower resilience scores and higher use of denial, substance use, and behavioral disengagement. Conclusion: To decrease both cognitive and evening physical fatigue, clinicians need to assess for relevant stressors and initiate interventions to increase resilience and the use of engagement coping strategies. Additional research is warranted on the relative contribution of various social determinants of health to both cognitive and physical fatigue in oncology patients receiving chemotherapy.
KW - Cancer
KW - chemotherapy
KW - cognitive impairment
KW - coping
KW - fatigue
KW - resilience
KW - stress
UR - http://www.scopus.com/inward/record.url?scp=85143849826&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85143849826&partnerID=8YFLogxK
U2 - 10.1016/j.jpainsymman.2022.11.017
DO - 10.1016/j.jpainsymman.2022.11.017
M3 - Article
C2 - 36423801
AN - SCOPUS:85143849826
SN - 0885-3924
VL - 65
SP - 203
EP - 215
JO - Journal of Pain and Symptom Management
JF - Journal of Pain and Symptom Management
IS - 3
ER -