HIV-1 prevention for HIV-1 serodiscordant couples

Kathryn Curran; Jared M. Baeten; Thomas J. Coates; Ann Kurth; Nelly R. Mugo; Connie Celum

doi:10.1007/s11904-012-0114-z

HIV-1 prevention for HIV-1 serodiscordant couples

Kathryn Curran, Jared M. Baeten, Thomas J. Coates, Ann Kurth, Nelly R. Mugo, Connie Celum

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Research output: Contribution to journal › Article › peer-review

Abstract

A substantial proportion of HIV-1 infected individuals in sub-Saharan Africa are in stable relationships with HIV-1 uninfected partners, and HIV-1 serodiscordant couples thus represent an important target population for HIV-1 prevention. Couple-based HIV-1 testing and counseling facilitates identification of HIV-1 serodiscordant couples, counseling about risk reduction, and referrals to HIV-1 treatment, reproductive health services, and support services. Maximizing HIV-1 prevention for HIV-1 serodiscordant couples requires a combination of strategies, including counseling about condoms, sexual risk, fertility, contraception, and the clinical and prevention benefits of antiretroviral therapy (ART) for the HIV-1-infected partner; provision of clinical care and ART for the HIV-1-infected partner; antenatal care and services to prevent mother-to-child transmission for HIV-1-infected pregnant women; male circumcision for HIV-1-uninfected men; and, pending guidelines and demonstration projects, oral pre-exposure prophylaxis (PrEP) for HIV-1-uninfected partners.

Original language	English (US)
Pages (from-to)	160-170
Number of pages	11
Journal	Current HIV/AIDS Reports
Volume	9
Issue number	2
DOIs	https://doi.org/10.1007/s11904-012-0114-z
State	Published - Jun 2012

Keywords

ART
Africa
Antiretroviral
HIV-1 Serodiscordant couples
HIV-1 prevention
PrEP

ASJC Scopus subject areas

Virology
Infectious Diseases

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10.1007/s11904-012-0114-z

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title = "HIV-1 prevention for HIV-1 serodiscordant couples",

abstract = "A substantial proportion of HIV-1 infected individuals in sub-Saharan Africa are in stable relationships with HIV-1 uninfected partners, and HIV-1 serodiscordant couples thus represent an important target population for HIV-1 prevention. Couple-based HIV-1 testing and counseling facilitates identification of HIV-1 serodiscordant couples, counseling about risk reduction, and referrals to HIV-1 treatment, reproductive health services, and support services. Maximizing HIV-1 prevention for HIV-1 serodiscordant couples requires a combination of strategies, including counseling about condoms, sexual risk, fertility, contraception, and the clinical and prevention benefits of antiretroviral therapy (ART) for the HIV-1-infected partner; provision of clinical care and ART for the HIV-1-infected partner; antenatal care and services to prevent mother-to-child transmission for HIV-1-infected pregnant women; male circumcision for HIV-1-uninfected men; and, pending guidelines and demonstration projects, oral pre-exposure prophylaxis (PrEP) for HIV-1-uninfected partners.",

keywords = "ART, Africa, Antiretroviral, HIV-1 Serodiscordant couples, HIV-1 prevention, PrEP",

author = "Kathryn Curran and Baeten, {Jared M.} and Coates, {Thomas J.} and Ann Kurth and Mugo, {Nelly R.} and Connie Celum",

note = "Funding Information: Funding: the Bill and Melinda Gates Foundation (47674) and the National Institutes of Health (R01 AI083034, R21 NR012663, and R01 MH095507).",

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doi = "10.1007/s11904-012-0114-z",

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AU - Mugo, Nelly R.

AU - Celum, Connie

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N2 - A substantial proportion of HIV-1 infected individuals in sub-Saharan Africa are in stable relationships with HIV-1 uninfected partners, and HIV-1 serodiscordant couples thus represent an important target population for HIV-1 prevention. Couple-based HIV-1 testing and counseling facilitates identification of HIV-1 serodiscordant couples, counseling about risk reduction, and referrals to HIV-1 treatment, reproductive health services, and support services. Maximizing HIV-1 prevention for HIV-1 serodiscordant couples requires a combination of strategies, including counseling about condoms, sexual risk, fertility, contraception, and the clinical and prevention benefits of antiretroviral therapy (ART) for the HIV-1-infected partner; provision of clinical care and ART for the HIV-1-infected partner; antenatal care and services to prevent mother-to-child transmission for HIV-1-infected pregnant women; male circumcision for HIV-1-uninfected men; and, pending guidelines and demonstration projects, oral pre-exposure prophylaxis (PrEP) for HIV-1-uninfected partners.

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HIV-1 prevention for HIV-1 serodiscordant couples

Abstract

Keywords

ASJC Scopus subject areas

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