HIV-1 transmission in injection paraphernalia: Heating drug solutions may inactivate HIV-1

Michael C. Clatts, Robert Heimer, Nadia Abdala, Lloyd A. Goldsamt, Jo L. Sotheran, Kenneth T. Anderson, Toni M. Gallo, Lee D. Hoffer, Pellegrino A. Luciano, Tassos Kyriakides

Research output: Contribution to journalArticle

Abstract

In response to recent concerns about risk of HIV-1 transmission from drug injection paraphernalia such as cookers, ethnographic methods were used to develop a descriptive typology of the paraphernalia and practices used to prepare and inject illegal drugs. Observational data were then applied in laboratory studies in which a quantitative HIV-1 microculture assay was used to measure the recovery of infectious HIV-1 in cookers. HIV-1 survival inside cookers was a function of the temperature achieved during preparation of drug solutions; HIV-1 was inactivated once temperature exceeded, on average, 65°C. Although different types of cookers, volumes, and heat sources affected survival times, heating cookers 15 seconds or longer reduced viable HIV-1 below detectable levels.

Original languageEnglish (US)
Pages (from-to)194-199
Number of pages6
JournalJournal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Volume22
Issue number2
DOIs
StatePublished - Oct 1 1999

Keywords

  • Drug injection practices
  • Ethnography
  • HIV-1 transmission

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Virology

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  • Cite this

    Clatts, M. C., Heimer, R., Abdala, N., Goldsamt, L. A., Sotheran, J. L., Anderson, K. T., Gallo, T. M., Hoffer, L. D., Luciano, P. A., & Kyriakides, T. (1999). HIV-1 transmission in injection paraphernalia: Heating drug solutions may inactivate HIV-1. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 22(2), 194-199. https://doi.org/10.1097/00126334-199910010-00013