Hold on Tight: Lagging-Strand DNA Polymerases Synthesize Multiple Okazaki Fragments without Letting Go

Vanessa Kellner; Duncan J. Smith

doi:10.1016/j.molcel.2020.09.010

Hold on Tight: Lagging-Strand DNA Polymerases Synthesize Multiple Okazaki Fragments without Letting Go

Vanessa Kellner, Duncan J. Smith

Biology and Genomics

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Kapadia et al. (2020) use an innovative single-molecule imaging approach in yeast cells to measure chromatin association of individual replisome subunits, thereby challenging the notion that lagging-strand DNA polymerases frequently dissociate from replisomes during DNA replication in vivo.

Original language	English (US)
Pages (from-to)	6-8
Number of pages	3
Journal	Molecular Cell
Volume	80
Issue number	1
DOIs	https://doi.org/10.1016/j.molcel.2020.09.010
State	Published - Oct 1 2020

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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10.1016/j.molcel.2020.09.010

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title = "Hold on Tight: Lagging-Strand DNA Polymerases Synthesize Multiple Okazaki Fragments without Letting Go",

abstract = "Kapadia et al. (2020) use an innovative single-molecule imaging approach in yeast cells to measure chromatin association of individual replisome subunits, thereby challenging the notion that lagging-strand DNA polymerases frequently dissociate from replisomes during DNA replication in vivo.",

author = "Vanessa Kellner and Smith, {Duncan J.}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

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AU - Smith, Duncan J.

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Hold on Tight: Lagging-Strand DNA Polymerases Synthesize Multiple Okazaki Fragments without Letting Go

Abstract

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