Hold on Tight: Lagging-Strand DNA Polymerases Synthesize Multiple Okazaki Fragments without Letting Go

Vanessa Kellner, Duncan J. Smith

Research output: Contribution to journalArticlepeer-review

Abstract

Kapadia et al. (2020) use an innovative single-molecule imaging approach in yeast cells to measure chromatin association of individual replisome subunits, thereby challenging the notion that lagging-strand DNA polymerases frequently dissociate from replisomes during DNA replication in vivo.

Original languageEnglish (US)
Pages (from-to)6-8
Number of pages3
JournalMolecular Cell
Volume80
Issue number1
DOIs
StatePublished - Oct 1 2020

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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