Holographic Molecular Binding Assays

David G. Grier, Rushna Quddus, Kaitlynn Snyder, Lauren E. Altman, Kent Kirshenbaum

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Holographic particle characterization yields the diameter of individual colloidal spheres with nanometer precision and can resolve probe beads growing as molecules bind to their surfaces. We demonstrate label-free holographic assays for antibodies and for antigenic proteins from pathogenic viruses, including SARS-CoV-2 and H1N1.

Original languageEnglish (US)
Title of host publicationDigital Holography and Three-Dimensional Imaging, DH 2022
PublisherOptica Publishing Group (formerly OSA)
ISBN (Electronic)9781957171128
StatePublished - 2022
EventDigital Holography and Three-Dimensional Imaging, DH 2022 - Cambridge, United Kingdom
Duration: Aug 1 2022Aug 4 2022

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701


ConferenceDigital Holography and Three-Dimensional Imaging, DH 2022
Country/TerritoryUnited Kingdom

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials


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