How two meters of DNA fit into a cell nucleus: Polymer models with topological constraints and experimental data

A. Yu Grosberg

    Research output: Contribution to journalArticle

    Abstract

    A recent experiment has confirmed the theoretical prediction of the fractal properties of DNA packaged in the cell nucleus of eukaryotes, particularly in interphase chromosomes. In this study, both the main theoretical ideas and the experimental results are presented in a compact form. Other properties of chromosomes, that is, the so-called territories, which allow for a natural explanation through the concepts of polymer physics, are discussed. At the end, some open questions are formulated.

    Original languageEnglish (US)
    Pages (from-to)1-10
    Number of pages10
    JournalPolymer Science - Series C
    Volume54
    Issue number1
    DOIs
    StatePublished - Sep 2012

    ASJC Scopus subject areas

    • Chemistry(all)
    • Polymers and Plastics
    • Materials Chemistry

    Fingerprint Dive into the research topics of 'How two meters of DNA fit into a cell nucleus: Polymer models with topological constraints and experimental data'. Together they form a unique fingerprint.

  • Cite this