Human histologic evidence of reosseointegration around an implant affected with peri-implantitis following decontamination with sterile saline and antiseptics: A case history report

Paul Fletcher, Daniel Deluiz, Eduardo M.B. Tinoco, John L. Ricci, Dennis P. Tarnow, Justine Monnerat Tinoco

Research output: Contribution to journalArticle


The treatment of peri-implant disease is one of the most controversial topics in implant dentistry. The multifactorial etiology and the myriad proposed techniques for managing the problem make successful decontamination of an implant surface affected by peri-implantitis one of the more unpredictable challenges dental practitioners have to face. This article presents the first known published case report demonstrating human histologic evidence of reosseointegration using a plastic curette for mechanical debridement and dilute sodium hypochlorite, hydrogen peroxide, and sterile saline for chemical detoxification. Guided bone regeneration in the infrabony component of the peri-implantitis lesion was accomplished using calcium sulfate and bovine bone as grafting materials and a porcine collagen barrier for connective tissue and epithelial exclusion.

Original languageEnglish (US)
Pages (from-to)498-508
Number of pages11
JournalInternational Journal of Periodontics and Restorative Dentistry
Issue number4
StatePublished - Jan 1 2017


ASJC Scopus subject areas

  • Oral Surgery
  • Periodontics

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