Hydrogen-bonded frameworks for conformational analysis of reactive substrates

Alexandra M. Dillon; Alexander G. Shtukenberg; Krystyna M. Demkiw; K. A. Woerpel; Michael D. Ward

doi:10.1039/d4cc03430a

Hydrogen-bonded frameworks for conformational analysis of reactive substrates

Alexandra M. Dillon, Alexander G. Shtukenberg, Krystyna M. Demkiw, K. A. Woerpel, Michael D. Ward

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Guanidinium organosulfonate (GS) hydrogen-bonded host frameworks were used to trap α-halopropiophenones and α-halocyclooctanones to determine their molecular structure by single crystal X-ray diffraction. The majority of encapsulated guest molecules adopted conformations expected from computational analysis and stereochemical outcomes of Grignard reactions.

Original language	English (US)
Pages (from-to)	11770-11773
Number of pages	4
Journal	Chemical Communications
Volume	60
Issue number	82
DOIs	https://doi.org/10.1039/d4cc03430a
State	Published - Sep 25 2024

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Catalysis
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

Access to Document

10.1039/d4cc03430a

Cite this

@article{b3598a22b4fb4efbaa308ede7b981dd7,

title = "Hydrogen-bonded frameworks for conformational analysis of reactive substrates",

abstract = "Guanidinium organosulfonate (GS) hydrogen-bonded host frameworks were used to trap α-halopropiophenones and α-halocyclooctanones to determine their molecular structure by single crystal X-ray diffraction. The majority of encapsulated guest molecules adopted conformations expected from computational analysis and stereochemical outcomes of Grignard reactions.",

author = "Dillon, {Alexandra M.} and Shtukenberg, {Alexander G.} and Demkiw, {Krystyna M.} and Woerpel, {K. A.} and Ward, {Michael D.}",

note = "Publisher Copyright: {\textcopyright} 2024 The Royal Society of Chemistry.",

year = "2024",

month = sep,

day = "25",

doi = "10.1039/d4cc03430a",

language = "English (US)",

volume = "60",

pages = "11770--11773",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "82",

}

TY - JOUR

T1 - Hydrogen-bonded frameworks for conformational analysis of reactive substrates

AU - Dillon, Alexandra M.

AU - Shtukenberg, Alexander G.

AU - Demkiw, Krystyna M.

AU - Woerpel, K. A.

AU - Ward, Michael D.

PY - 2024/9/25

Y1 - 2024/9/25

N2 - Guanidinium organosulfonate (GS) hydrogen-bonded host frameworks were used to trap α-halopropiophenones and α-halocyclooctanones to determine their molecular structure by single crystal X-ray diffraction. The majority of encapsulated guest molecules adopted conformations expected from computational analysis and stereochemical outcomes of Grignard reactions.

AB - Guanidinium organosulfonate (GS) hydrogen-bonded host frameworks were used to trap α-halopropiophenones and α-halocyclooctanones to determine their molecular structure by single crystal X-ray diffraction. The majority of encapsulated guest molecules adopted conformations expected from computational analysis and stereochemical outcomes of Grignard reactions.

UR - http://www.scopus.com/inward/record.url?scp=85205907251&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85205907251&partnerID=8YFLogxK

U2 - 10.1039/d4cc03430a

DO - 10.1039/d4cc03430a

M3 - Article

C2 - 39320845

AN - SCOPUS:85205907251

SN - 1359-7345

VL - 60

SP - 11770

EP - 11773

JO - Chemical Communications

JF - Chemical Communications

IS - 82

ER -

Hydrogen-bonded frameworks for conformational analysis of reactive substrates

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this