Hydrogen bonding control of self-assembly: Simple isophthalic acid derivatives form cyclic hexameric aggregates

Ji Yang, Jean Luc Marendaz, Steven J. Geib, Andrew D. Hamilton

Research output: Contribution to journalArticle

Abstract

In this paper we demonstrate that six molecules of a functionalized isophthalic acid derivative form a cyclic aggregate stabilized by a network of 12 hydrogen bonds. The structure and stability of the aggregate were studied by X-ray crystallography, vapor phase osmometry and 1H NMR.

Original languageEnglish (US)
Pages (from-to)3665-3668
Number of pages4
JournalTetrahedron Letters
Volume35
Issue number22
DOIs
StatePublished - May 30 1994

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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