Hypertension Treatment in Blacks: Discussion of the U.S. Clinical Practice Guidelines

Stephen K. Williams, Joseph Ravenell, Sara Seyedali, Sam Nayef, Gbenga Ogedegbe

Research output: Contribution to journalReview articlepeer-review


Blacks are especially susceptible to hypertension (HTN) and its associated organ damage leading to adverse cardiovascular, cerebrovascular and renal outcomes. Accordingly, HTN is particularly significant in contributing to the black-white racial differences in health outcomes in the US. As such, in order to address these health disparities, practical clinical practice guidelines (CPGs) on how to treat HTN, specifically in blacks, are needed. This review article is a timely addition to the literature because the most recent U.S. CPG more explicitly emphasizes race into the algorithmic management of HTN. However, recent clinical research cautions that use of race as a proxy to determine therapeutic response to pharmaceutical agents may be erroneous. This review will address the implications of the use of race in the hypertension CPGs. We will review the rationale behind the introduction of race into the U.S. CPG and the level of evidence that was available to justify this introduction. Finally, we will conclude with practical considerations in the treatment of HTN in blacks.

Original languageEnglish (US)
Pages (from-to)282-288
Number of pages7
JournalProgress in Cardiovascular Diseases
Issue number3
StatePublished - Nov 1 2016


  • African Americans
  • Blacks
  • Hypertension
  • Minorities

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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