IAPAC guidelines for optimizing the HIV care continuum for adults and adolescents

Linda Gail Bekker, Julio Montaner, Celso Ramos, Renslow Sherer, Francesca Celletti, Blayne Cutler, François Dabis, Reuben Granich, Alan Greenberg, Shira Goldenberg, Mark Hull, Thomas Kerr, Ann Kurth, Kenneth Mayer, Lisa Metsch, Nelly R. Mugo, Paula Munderi, Jean Nachega, Bohdan Nosyk, Jorge SaavedraTheresa Wolters, Benjamin Young, José M. Zuniga, Bruce Agins, K. Rivet Amico, Josip Begovac, Chris Beyrer, Pedro Cahn, Gus Cairns, Mardge Cohen, Kathleen Deering, Carlos Del Rio, Ricardo S. Diaz, Julia C. Dombrowski, Rupali Doshi, Wafaa El-Sadr, Donna Futterman, Anna Maria Geretti, Giovanni Guaraldi, Jim Halloran, Christopher M. Gordon, Shoshana Kahana, Javier Lama, Viviane Dias Lima, Nathan Linsk, Antonella D Arminio Monforte, Mark Nelson, Eyerusalem Negussie, Praphan Phanuphak, James Scott, Douglas Shaffer, Kate Shannon, Anne Spaulding, Carlos Valerio, Zunyou Wu, Anna Zakowicz, Carmen Zorrilla

Research output: Contribution to journalReview articlepeer-review


Background: An estimated 50% of people living with HIV (PLHIV) globally are unaware of their status. Among those who know their HIV status, many do not receive antiretroviral therapy (ART) in a timely manner, fail to remain engaged in care, or do not achieve sustained viral suppression. Barriers across the HIV care continuum prevent PLHIV from achieving the therapeutic and preventive effects of ART. Methods: A systematic literature search was conducted, and 6132 articles, including randomized controlled trials, observational studies with or without comparators, cross-sectional studies, and descriptive documents, met the inclusion criteria. Of these, 1047 articles were used to generate 36 recommendations to optimize the HIV care continuum for adults and adolescents. Recommendations: Recommendations are provided for interventions to optimize the HIV care environment; increase HIV testing and linkage to care, treatment coverage, retention in care, and viral suppression; and monitor the HIV care continuum.

Original languageEnglish (US)
Pages (from-to)S3-S34
JournalJournal of the International Association of Providers of AIDS Care
StatePublished - Nov 1 2015


  • HIV
  • antiretroviral therapy
  • continuum of care
  • testing
  • viral suppression

ASJC Scopus subject areas

  • Immunology
  • Dermatology
  • Infectious Diseases


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