IBAD nanothick bioceramic incorporation on metallic implants for bone healing enhancement. From physico/chemical characterization to in-vivo performance evaluation

P. G. Coelho, J. E. Lemons

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Preliminary data on in-vivo performance of nanothick bioceramic IBAD-coated metallic implants showed an increase in both osteoblastic activity and mechanical properties for bone surrounding these implants. The purpose of this study was to characterize a thin-film bioceramic coating obtained by Ion Beam Assisted Deposition (IBAD) on Ti-6Al-4V implants and evaluate its in-vivo performance in an animal model. Control (Q) and IBAD-coated implants were analyzed by SEM, EDS, ion-milling + XPS for depth profiling, and thin-film XRD. 60 cylindrical implants were bilaterally placed in the tibias of 6 beagle dogs through sequenced surgical procedures and were biomechanically tested (torque) at 3 and 5 weeks in-vivo. No thin-film was detected by SEM, and the EDS spectra for IBAD coated implants showed Ca presence. XPS showed Ca, P, Si, C, and O at outer layers with variable Ca/P ratios as a function of depth. XRD spectra revealed an amorphous microstructure for IBAD implants. Biomechanical tests showed that IBAD-coated implants had superior fixation competence compared to control implants at 3 and 5 weeks in-vivo. According to the results, it was concluded that the nanothick surface coating enhanced the biological response of bone to implant, supporting opportunities for increased bone healing response in clinical practice.

Original languageEnglish (US)
Title of host publication2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005 Technical Proceedings
EditorsM. Laudon, B. Romanowicz
Pages316-319
Number of pages4
StatePublished - 2005
Event2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005 - Anaheim, CA, United States
Duration: May 8 2005May 12 2005

Publication series

Name2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005 Technical Proceedings

Other

Other2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005
CountryUnited States
CityAnaheim, CA
Period5/8/055/12/05

Keywords

  • Bioceramic
  • Biomechanical Testing
  • Characterization
  • IBAD
  • Thin-film

ASJC Scopus subject areas

  • Engineering(all)

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    Coelho, P. G., & Lemons, J. E. (2005). IBAD nanothick bioceramic incorporation on metallic implants for bone healing enhancement. From physico/chemical characterization to in-vivo performance evaluation. In M. Laudon, & B. Romanowicz (Eds.), 2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005 Technical Proceedings (pp. 316-319). (2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005 Technical Proceedings).