Identification of a novel HLA-A allele, HLA-A01:195, in a UAE national

Wael Abdrabou, Ini Isabée Witzel, Agnieszka Paduch, Guan Tay, Habiba Alsafar

Research output: Contribution to journalArticlepeer-review


A novel human leucocyte antigen (HLA)-A allele, HLA-A01:195, was identified by sequence-based typing (SBT) in a UAE national subject. The novel allele is identical to its closest known allele, HLA-A01:01:01:01, in exon 2, 3 and 4, except for a single nucleotide mutation of A to G at position 442 in exon 3 (codon 124 in the α2 domain of the α chain of the mature protein). This A to G mutation results in an amino acid change of isoleucine #124 to valine.

Original languageEnglish (US)
Pages (from-to)605-608
Number of pages4
JournalHuman Immunology
Issue number7
StatePublished - Jul 1 2016


  • Arab genetics
  • HLA-A01:195
  • Novel HLA-A allele
  • Sequence based typing

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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