Identification of unique bacterial gene segments from Streptococcus mutans with potential relevance to dental caries by subtraction DNA hybridization

Deepak Saxena, Yihong Li, Page W. Caufield

Research output: Contribution to journalArticle


Using DNA subtractive hybridization, 49 unique gene segments were identified from a strain of Streptococcus mutans that was isolated from a patient with severe early childhood caries (S-ECC). Further hybridization with DNA from other S. mutans strains isolated from both caries-active and caries-free subjects yielded five unique sequences of DNA common to strains associated with S-ECC.

Original languageEnglish (US)
Pages (from-to)3508-3511
Number of pages4
JournalJournal of Clinical Microbiology
Issue number7
StatePublished - Jul 1 2005


ASJC Scopus subject areas

  • Microbiology (medical)

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