TY - GEN
T1 - Imaging in biological tissues by means of diffraction tomography with photon density waves
AU - Hielscher, Andreas H.
AU - Tittel, Frank K.
AU - Jacques, Steven L.
N1 - Funding Information:
This work was supported in part by the Department of Energy and the Robert A. Welch Foundation.
Publisher Copyright:
© 1995 SPIE. All rights reserved.
PY - 1995/1/31
Y1 - 1995/1/31
N2 - In biological tissues it is possible to generate photon density waves with wavelength below 5 cm. When these kind of waves encounter optical inhomogeneities with diameters in the mm- and cm-range, typical scattering effects occur. These scattering effect can be compared to the well known effect of ultrasound scattering. Ultrasound gets scattered at regions with different compressibility and density, while photon density waves are scattered at regions with different absorption and scattering coefficient. In this study, analytical solutions for the time dependent photon diffusion equation are used to estimate photon density wave diffraction effects caused by spherical optical inhomogeneities. The detectability of tumors and hemorrhages in the brain, based on the diffraction pattern generated by these heterogeneities, is discussed in detail.
AB - In biological tissues it is possible to generate photon density waves with wavelength below 5 cm. When these kind of waves encounter optical inhomogeneities with diameters in the mm- and cm-range, typical scattering effects occur. These scattering effect can be compared to the well known effect of ultrasound scattering. Ultrasound gets scattered at regions with different compressibility and density, while photon density waves are scattered at regions with different absorption and scattering coefficient. In this study, analytical solutions for the time dependent photon diffusion equation are used to estimate photon density wave diffraction effects caused by spherical optical inhomogeneities. The detectability of tumors and hemorrhages in the brain, based on the diffraction pattern generated by these heterogeneities, is discussed in detail.
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U2 - 10.1117/12.200865
DO - 10.1117/12.200865
M3 - Conference contribution
AN - SCOPUS:33744604888
VL - 2326
T3 - Proceedings of SPIE - The International Society for Optical Engineering
SP - 75
EP - 85
BT - Photon Transport in Highly Scattering Tissue 1994
T2 - Photon Transport in Highly Scattering Tissue 1994
Y2 - 6 September 1994 through 10 September 1994
ER -