In conclusion, the future of glaucoma imaging for early glaucoma diagnosis and change detection must assess both the structure and function of the optic nerve, including ganglion cell bodies and axons. We believe that structural assessment alone may not be adequate for early detection of glaucoma because of the overlap of ONH topography and NFL thickness between normal individuals and those with glaucoma; however, we expect these techniques to be excellent for detection of the progression of glaucomatous damage. We expect some overlap in functional parameters as well. We forsee the need for objective quantitative functional tests in conjunction with objective, quantitative structural assessment. Through the use of these advanced technologies, we expect that clinicians will have the means for earlier and more reliable detection of glaucoma and its progression.
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