Imaging of the retinal nerve fibre layer with spectral domain optical coherence tomography for glaucoma diagnosis

Kyung Rim Sung, Jong S. Kim, Gadi Wollstein, Lindsey Folio, Michael S. Kook, Joel S. Schuman

    Research output: Contribution to journalReview article

    Abstract

    Optical coherence tomography (OCT) techniques have been applied to develop a new generation of the technology, called spectral domain (SD) or Fourier domain (FD) OCT. The commercially available SD-OCT technology offers benefits over the conventional time domain (TD) OCT such as a scanning speed up to 200 times faster and higher axial resolution (3 to 6 mm). Overall, SD-OCT offers improved performance in terms of reproducibility. SD-OCT has a level of discriminating capability, between healthy and perimetric glaucoma eyes similar to that obtained with TD-OCT. Furthermore, the capabilities and features of SD-OCT are rapidly evolving, mainly due to three-dimensional imaging and image rendering. More sophisticated approaches for macular and optic disc assessment are expected to be employed in clinical practice. Analysis software should be further refined for interpretation of SD-OCT images in order to enhance the sensitivity and specificity of glaucoma diagnostics. Most importantly for SD-OCT is determination of its ability to diagnostic structural glaucomatous progression. Considering the recent launch time of the commercially available SD-OCT and slow progressing characteristic of glaucoma, we must wait for longitudinal SD-OCT data, with a long enough follow-up, to become available.

    Original languageEnglish (US)
    Pages (from-to)909-914
    Number of pages6
    JournalBritish Journal of Ophthalmology
    Volume95
    Issue number7
    DOIs
    StatePublished - Jul 1 2011

      Fingerprint

    ASJC Scopus subject areas

    • Ophthalmology
    • Sensory Systems
    • Cellular and Molecular Neuroscience

    Cite this