Imaging the High-risk Prostate Cancer Patient: Current and Future Approaches to Staging

Marc A. Bjurlin, Baris Turkbey, Andrew B. Rosenkrantz, Sonia Gaur, Peter L. Choyke, Samir S. Taneja

    Research output: Contribution to journalReview article

    Abstract

    Imaging is critically important for the diagnosis, staging, and management of men with high-risk prostate cancer. Conventional imaging modalities have been employed for local and metastatic staging with limited performance. Sodium fluoride positron emission tomography is recommended when there is high suspicion of bone metastases despite a negative or indeterminate bone scan. Magnetic resonance imaging has advantages in local staging but its value depends on the extent of disease. Whole-body positron emission tomography/magnetic resonance imaging could provide both local and distant staging. None of the existing positron emission tomography agents are recommended in practice guidelines; however, among them, prostate-specific membrane antigen-based tracers seem to hold the most promise based on sensitivity and specificity.

    Original languageEnglish (US)
    Pages (from-to)3-12
    Number of pages10
    JournalUrology
    Volume116
    DOIs
    StatePublished - Jun 2018

    ASJC Scopus subject areas

    • Urology

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  • Cite this

    Bjurlin, M. A., Turkbey, B., Rosenkrantz, A. B., Gaur, S., Choyke, P. L., & Taneja, S. S. (2018). Imaging the High-risk Prostate Cancer Patient: Current and Future Approaches to Staging. Urology, 116, 3-12. https://doi.org/10.1016/j.urology.2017.12.001