Impact of drug abuse treatment modalities on adherence to ART/HAART among a cohort of HIV seropositive women

Farzana Kapadia; David Vlahov; Yingfeng Wu; Mardge H. Cohen; Ruth M. Greenblatt; Andrea A. Howard; Judith A. Cook; Lakshmi Goparaju; Elizabeth Golub; Jean Richardson; Tracey E. Wilson

doi:10.1080/00952990701877052

Impact of drug abuse treatment modalities on adherence to ART/HAART among a cohort of HIV seropositive women

Farzana Kapadia, David Vlahov, Yingfeng Wu, Mardge H. Cohen, Ruth M. Greenblatt, Andrea A. Howard, Judith A. Cook, Lakshmi Goparaju, Elizabeth Golub, Jean Richardson, Tracey E. Wilson

Research output: Contribution to journal › Article › peer-review

Abstract

Methadone maintenance is associated with improved adherence to antiretroviral therapies among HIV-positive illicit drug users; however, little information exists on whether adherence is associated with different drug abuse treatment modalities. Using longitudinal data from the Women's Interagency HIV Study, we evaluated the relationship between drug abuse treatment modality and adherence to antiretroviral therapies. In prospective analyses, individuals who reported accessing any drug abuse treatment program were more likely to report adherence to antiretroviral regimens ≥ 95% of the time (AOR = 1.39, 95% CI = 1.01-1.92). Involvement in either a medication-based or medication-free program was similarly associated with improved adherence. Drug abuse treatment programs, irrespective of modality, are associated with improved adherence to antiretroviral therapies among drug users. Concerted efforts to enroll individuals with drug use histories in treatment programs are warranted to improve HIV disease outcomes.

Original language	English (US)
Pages (from-to)	161-170
Number of pages	10
Journal	American Journal of Drug and Alcohol Abuse
Volume	34
Issue number	2
DOIs	https://doi.org/10.1080/00952990701877052
State	Published - Mar 2008

Keywords

Adherence
Antiretroviral therapy
Drug abuse treatment modality
Human immunodeficiency virus

ASJC Scopus subject areas

Medicine (miscellaneous)
Clinical Psychology
Psychiatry and Mental health

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10.1080/00952990701877052

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Kapadia, F., Vlahov, D., Wu, Y., Cohen, M. H., Greenblatt, R. M., Howard, A. A., Cook, J. A., Goparaju, L., Golub, E., Richardson, J., & Wilson, T. E. (2008). Impact of drug abuse treatment modalities on adherence to ART/HAART among a cohort of HIV seropositive women. American Journal of Drug and Alcohol Abuse, 34(2), 161-170. https://doi.org/10.1080/00952990701877052

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title = "Impact of drug abuse treatment modalities on adherence to ART/HAART among a cohort of HIV seropositive women",

abstract = "Methadone maintenance is associated with improved adherence to antiretroviral therapies among HIV-positive illicit drug users; however, little information exists on whether adherence is associated with different drug abuse treatment modalities. Using longitudinal data from the Women's Interagency HIV Study, we evaluated the relationship between drug abuse treatment modality and adherence to antiretroviral therapies. In prospective analyses, individuals who reported accessing any drug abuse treatment program were more likely to report adherence to antiretroviral regimens ≥ 95% of the time (AOR = 1.39, 95% CI = 1.01-1.92). Involvement in either a medication-based or medication-free program was similarly associated with improved adherence. Drug abuse treatment programs, irrespective of modality, are associated with improved adherence to antiretroviral therapies among drug users. Concerted efforts to enroll individuals with drug use histories in treatment programs are warranted to improve HIV disease outcomes.",

keywords = "Adherence, Antiretroviral therapy, Drug abuse treatment modality, Human immunodeficiency virus",

author = "Farzana Kapadia and David Vlahov and Yingfeng Wu and Cohen, {Mardge H.} and Greenblatt, {Ruth M.} and Howard, {Andrea A.} and Cook, {Judith A.} and Lakshmi Goparaju and Elizabeth Golub and Jean Richardson and Wilson, {Tracey E.}",

note = "Funding Information: Data in this manuscript were collected by the Women{\textquoteright}s Interagency HIV Study (WIHS) Collaborative Study Group with centers (Principal Investigators) at New York City/Bronx Consortium (Kathryn Anastos); Brooklyn, NY (Howard Minkoff); Washington DC Metropolitan Consortium (Mary Young); The Connie Wofsy Study Consortium of Northern California (Ruth Greenblatt); Los Angeles County/Southern California Consortium (Alexandra Levine); Chicago Consortium (Mardge Cohen); Data Coordinating Center (Alvaro Munoz). The WIHS is funded by the National Institute of Allergy and Infectious Diseases, with supplemental funding from the National Cancer Institute, the National Institute of Child Health & Human Development, The National Institute on Drug Abuse, and the National Institute of Craniofacial and Dental Research. U01-AI-35004, U01-AI-31834, U01-AI-34994, U01-AI-34989, U01-HD-32632, U01-AI-34993, U01-AI-42590, M01-RR00079, and M01-RR00083.",

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doi = "10.1080/00952990701877052",

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AU - Kapadia, Farzana

AU - Vlahov, David

AU - Wu, Yingfeng

AU - Cohen, Mardge H.

AU - Greenblatt, Ruth M.

AU - Howard, Andrea A.

AU - Cook, Judith A.

AU - Goparaju, Lakshmi

AU - Golub, Elizabeth

AU - Richardson, Jean

AU - Wilson, Tracey E.

N1 - Funding Information: Data in this manuscript were collected by the Women’s Interagency HIV Study (WIHS) Collaborative Study Group with centers (Principal Investigators) at New York City/Bronx Consortium (Kathryn Anastos); Brooklyn, NY (Howard Minkoff); Washington DC Metropolitan Consortium (Mary Young); The Connie Wofsy Study Consortium of Northern California (Ruth Greenblatt); Los Angeles County/Southern California Consortium (Alexandra Levine); Chicago Consortium (Mardge Cohen); Data Coordinating Center (Alvaro Munoz). The WIHS is funded by the National Institute of Allergy and Infectious Diseases, with supplemental funding from the National Cancer Institute, the National Institute of Child Health & Human Development, The National Institute on Drug Abuse, and the National Institute of Craniofacial and Dental Research. U01-AI-35004, U01-AI-31834, U01-AI-34994, U01-AI-34989, U01-HD-32632, U01-AI-34993, U01-AI-42590, M01-RR00079, and M01-RR00083.

PY - 2008/3

Y1 - 2008/3

N2 - Methadone maintenance is associated with improved adherence to antiretroviral therapies among HIV-positive illicit drug users; however, little information exists on whether adherence is associated with different drug abuse treatment modalities. Using longitudinal data from the Women's Interagency HIV Study, we evaluated the relationship between drug abuse treatment modality and adherence to antiretroviral therapies. In prospective analyses, individuals who reported accessing any drug abuse treatment program were more likely to report adherence to antiretroviral regimens ≥ 95% of the time (AOR = 1.39, 95% CI = 1.01-1.92). Involvement in either a medication-based or medication-free program was similarly associated with improved adherence. Drug abuse treatment programs, irrespective of modality, are associated with improved adherence to antiretroviral therapies among drug users. Concerted efforts to enroll individuals with drug use histories in treatment programs are warranted to improve HIV disease outcomes.

AB - Methadone maintenance is associated with improved adherence to antiretroviral therapies among HIV-positive illicit drug users; however, little information exists on whether adherence is associated with different drug abuse treatment modalities. Using longitudinal data from the Women's Interagency HIV Study, we evaluated the relationship between drug abuse treatment modality and adherence to antiretroviral therapies. In prospective analyses, individuals who reported accessing any drug abuse treatment program were more likely to report adherence to antiretroviral regimens ≥ 95% of the time (AOR = 1.39, 95% CI = 1.01-1.92). Involvement in either a medication-based or medication-free program was similarly associated with improved adherence. Drug abuse treatment programs, irrespective of modality, are associated with improved adherence to antiretroviral therapies among drug users. Concerted efforts to enroll individuals with drug use histories in treatment programs are warranted to improve HIV disease outcomes.

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KW - Drug abuse treatment modality

KW - Human immunodeficiency virus

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Impact of drug abuse treatment modalities on adherence to ART/HAART among a cohort of HIV seropositive women

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Keywords

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