TY - JOUR
T1 - Impact of implant thread design on insertion torque and osseointegration
T2 - a preclinical model
AU - Benalcázar-Jalkh, Ernesto B.
AU - Nayak, Vasudev Vivekanand
AU - Gory, Christina
AU - Marquez-Guzman, Andres
AU - Bergamo, Edmara T.P.
AU - Tovar, Nick
AU - Coelho, Paulo G.
AU - Bonfante, Estevam A.
AU - Witek, Lukasz
N1 - Publisher Copyright:
© Medicina Oral S. L.
PY - 2023/1
Y1 - 2023/1
N2 - Background: Successful osseointegration of endosteal dental implants has been attributed to implant design, including the macro-, micro-and nano-geometric properties. Based on current literature pertaining to implant design, the resultant cellular and bone healing response is unknown when the thread thickness of the implants is increased, resulting in an increased contact area in implants designed with healing chambers. The aim of this study was to evaluate the effect of two implant designs with different thread profiles on the osseointegration parameters and implant stability at 3-and 6-weeks in vivo using a well-established preclinical dog model. Material and Methods: A total of 48 type V Ti alloy implants were divided in two groups according to their thread design (D1 = +0.1x/mm and D2 = +0.15x/mm) and placed in an interpolated fashion into the radii of six beagles. Insertion torque was measured at time of placement, radii were extracted for histological processing following 3-and 6-week healing intervals. Histologic and histomorphometric analyses were performed in terms of bone to implant contact (%BIC) and bone area fraction occupancy within implant threads (%BAFO). Statistical analyses were performed through a linear mixed model with fixed factors of time and implant thread design. Results: Surface roughness analysis demonstrated no significant differences in Sa and Sq between D1 and D2 implant designs, which confirmed that both implant designs were homogenous except for their respective thread profiles. For insertion torque, statistically significant lower values were recorded for D1 in comparison to D2 (59.6 ± 11.1 and 78.9 ± 10.1 N⋅cm, respectively). Furthermore, there were no significant differences with respect to his-tological analysis and histomorphometric parameters, between D1 and D2 at both time points. Conclusions: Both thread profiles presented equivalent potential to successfully osseointegrate in the osteotomies, with D2 yielding higher mechanical retention upon placement without detrimental bone resorption.
AB - Background: Successful osseointegration of endosteal dental implants has been attributed to implant design, including the macro-, micro-and nano-geometric properties. Based on current literature pertaining to implant design, the resultant cellular and bone healing response is unknown when the thread thickness of the implants is increased, resulting in an increased contact area in implants designed with healing chambers. The aim of this study was to evaluate the effect of two implant designs with different thread profiles on the osseointegration parameters and implant stability at 3-and 6-weeks in vivo using a well-established preclinical dog model. Material and Methods: A total of 48 type V Ti alloy implants were divided in two groups according to their thread design (D1 = +0.1x/mm and D2 = +0.15x/mm) and placed in an interpolated fashion into the radii of six beagles. Insertion torque was measured at time of placement, radii were extracted for histological processing following 3-and 6-week healing intervals. Histologic and histomorphometric analyses were performed in terms of bone to implant contact (%BIC) and bone area fraction occupancy within implant threads (%BAFO). Statistical analyses were performed through a linear mixed model with fixed factors of time and implant thread design. Results: Surface roughness analysis demonstrated no significant differences in Sa and Sq between D1 and D2 implant designs, which confirmed that both implant designs were homogenous except for their respective thread profiles. For insertion torque, statistically significant lower values were recorded for D1 in comparison to D2 (59.6 ± 11.1 and 78.9 ± 10.1 N⋅cm, respectively). Furthermore, there were no significant differences with respect to his-tological analysis and histomorphometric parameters, between D1 and D2 at both time points. Conclusions: Both thread profiles presented equivalent potential to successfully osseointegrate in the osteotomies, with D2 yielding higher mechanical retention upon placement without detrimental bone resorption.
KW - Thread design
KW - dental implants
KW - implant stability
KW - microgeometry
KW - osseointegration
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U2 - 10.4317/medoral.25576
DO - 10.4317/medoral.25576
M3 - Article
C2 - 36173722
AN - SCOPUS:85145242450
SN - 1698-4447
VL - 28
SP - e48-e55
JO - Medicina Oral Patologia Oral y Cirugia Bucal
JF - Medicina Oral Patologia Oral y Cirugia Bucal
IS - 1
M1 - 25576
ER -