In vivo characterization of bone ingrowth into scaffolds with controlled architectures using micro-CT

J. L. Simon, T. Dutta Roy, J. R. Parsons, E. D. Rekow, V. P. Thompson, J. Yoo, J. L. Ricci

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The use of microcomputer tomography (micro-CT) for in vivo characterization of bone ingrowth into a scaffold in a rabbit trephine defect was discussed. The configurations of 100% hydroxyapatite (HA) scaffolds were printed and evaluated at 8 and 16 weeks. The scaffolds were 8 mm in diameter and 3 mm thick, with 15% bulk porosity and 20 μm average pore size. Group 1 scaffold architechture contained 50 μm x 500 μm " blind end" channels and group 2 contained "waffle like" architecture. It was observed that Micro-CT images of the scaffolds showed extensive bone ingrowth into both groups at 8 weeks.

Original languageEnglish (US)
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Publication series

NameTransactions - 7th World Biomaterials Congress

Other

OtherTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period5/17/045/21/04

ASJC Scopus subject areas

  • Engineering(all)

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    Simon, J. L., Dutta Roy, T., Parsons, J. R., Rekow, E. D., Thompson, V. P., Yoo, J., & Ricci, J. L. (2004). In vivo characterization of bone ingrowth into scaffolds with controlled architectures using micro-CT. In Transactions - 7th World Biomaterials Congress (Transactions - 7th World Biomaterials Congress).