Incorporation of unnatural amino acids for synthetic biology

Natalya Voloshchuk; Jin Kim Montclare

doi:10.1039/b909200p

Incorporation of unnatural amino acids for synthetic biology

Natalya Voloshchuk, Jin Kim Montclare

Chemical and Biomolecular Engineering

Research output: Contribution to journal › Review article › peer-review

Abstract

The challenge of synthetic biology lies in the construction of artificial cellular systems. This requires the development of modular "parts" that can be integrated into living systems to elicit an artificial, yet programmed, response or function. The development of methods to engineer proteins bearing unnatural amino acids (UAAs) provides essential components that may address this challenge. Here we review the emerging strategies for incorporating UAAs into proteins with the endgame of engineering artificial cells and organisms.

Original language	English (US)
Pages (from-to)	65-80
Number of pages	16
Journal	Molecular BioSystems
Volume	6
Issue number	1
DOIs	https://doi.org/10.1039/b909200p
State	Published - 2009

ASJC Scopus subject areas

Biotechnology
Molecular Biology

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10.1039/b909200p

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Incorporation of unnatural amino acids for synthetic biology

Abstract

ASJC Scopus subject areas

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