Inhibition of Protein-Protein Interactions by Peptide Mimics

Jorge Becerril; Johanna M. Rodriguez; Pauline N. Wyrembak; Andrew D. Hamilton

doi:10.1002/9780470972137.ch5

Inhibition of Protein-Protein Interactions by Peptide Mimics

Jorge Becerril, Johanna M. Rodriguez, Pauline N. Wyrembak, Andrew D. Hamilton

Chemistry

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Original language	English (US)
Title of host publication	Protein Surface Recognition
Subtitle of host publication	Approaches for Drug Discovery
Publisher	John Wiley and Sons
Pages	105-131
Number of pages	27
ISBN (Print)	9780470059050
DOIs	https://doi.org/10.1002/9780470972137.ch5
State	Published - Nov 30 2010

Keywords

Biological processes, and communication between proteins - specific surface interactions
Coactivator proteins, multiple repeats - conserved Leu-X-X-Leu-Leu (LXXLL) motif
Inhibitors of protein-protein interactions - allies in fight against HIV-1 epidemic
Nuclear estrogen receptor inhibition
Protein-protein interactions (PPIs) - normal cell function and regulating processes
Protein-protein interactions - mediated by binding epitope, residues as a-helix, β-turn or a β-sheet
Turns, common structural element - in PPIs, post-translational modifications and antibody recognition
p53/MDM2 interaction, another protein-protein interaction - in apoptotic pathway
protein-protein interaction inhibition - by peptide mimics
β-sheet, second major structural element - in globular proteins

ASJC Scopus subject areas

General Pharmacology, Toxicology and Pharmaceutics
General Biochemistry, Genetics and Molecular Biology

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10.1002/9780470972137.ch5

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keywords = "Biological processes, and communication between proteins - specific surface interactions, Coactivator proteins, multiple repeats - conserved Leu-X-X-Leu-Leu (LXXLL) motif, Inhibitors of protein-protein interactions - allies in fight against HIV-1 epidemic, Nuclear estrogen receptor inhibition, Protein-protein interactions (PPIs) - normal cell function and regulating processes, Protein-protein interactions - mediated by binding epitope, residues as a-helix, β-turn or a β-sheet, Turns, common structural element - in PPIs, post-translational modifications and antibody recognition, p53/MDM2 interaction, another protein-protein interaction - in apoptotic pathway, protein-protein interaction inhibition - by peptide mimics, β-sheet, second major structural element - in globular proteins",

author = "Jorge Becerril and Rodriguez, {Johanna M.} and Wyrembak, {Pauline N.} and Hamilton, {Andrew D.}",

year = "2010",

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language = "English (US)",

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TY - CHAP

T1 - Inhibition of Protein-Protein Interactions by Peptide Mimics

AU - Becerril, Jorge

AU - Rodriguez, Johanna M.

AU - Wyrembak, Pauline N.

AU - Hamilton, Andrew D.

PY - 2010/11/30

Y1 - 2010/11/30

KW - Biological processes, and communication between proteins - specific surface interactions

KW - Coactivator proteins, multiple repeats - conserved Leu-X-X-Leu-Leu (LXXLL) motif

KW - Inhibitors of protein-protein interactions - allies in fight against HIV-1 epidemic

KW - Nuclear estrogen receptor inhibition

KW - Protein-protein interactions (PPIs) - normal cell function and regulating processes

KW - Protein-protein interactions - mediated by binding epitope, residues as a-helix, β-turn or a β-sheet

KW - Turns, common structural element - in PPIs, post-translational modifications and antibody recognition

KW - p53/MDM2 interaction, another protein-protein interaction - in apoptotic pathway

KW - protein-protein interaction inhibition - by peptide mimics

KW - β-sheet, second major structural element - in globular proteins

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U2 - 10.1002/9780470972137.ch5

DO - 10.1002/9780470972137.ch5

M3 - Chapter

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SN - 9780470059050

SP - 105

EP - 131

BT - Protein Surface Recognition

PB - John Wiley and Sons

ER -

Inhibition of Protein-Protein Interactions by Peptide Mimics

Keywords

ASJC Scopus subject areas

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