Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines

Edwina C. Lerner, Ting Ting Zhang, David B. Knowles, Yimin Qian, Andrew D. Hamilton, Saïd M. Sebti

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Immunology and Microbiology

Biochemistry, Genetics and Molecular Biology

Medicine and Dentistry