Inhibitory deficits in Tourette's syndrome

Emily R. Stern, Clancy Blair, Bradley S. Peterson

Research output: Contribution to journalArticle

Abstract

A developmental approach to the study of psychopathology can broaden understanding of a wide variety of complex psychological disorders. This article reviews research on Tourette's syndrome (TS), a developmental disorder characterized by unwanted motor and vocal tics. Over the past decade, knowledge of the neurobiology and pathophysiology of TS has progressed rapidly. The application of brain imaging techniques, primarily magnetic resonance imaging, to the study of Tourette's has increased knowledge of structural and functional deficits in brain areas associated with behavioral and psychological disturbances in the disorder. By reviewing some of this work, we will describe one way in which knowledge of brain function in TS has both informed and been informed by a developmental science approach. In particular, we will consider the extent to which the cognitive and emotional development of persons with TS may be affected by specific neurobiological characteristics of the disorder.

Original languageEnglish (US)
Pages (from-to)9-18
Number of pages10
JournalDevelopmental Psychobiology
Volume50
Issue number1
DOIs
StatePublished - Jan 2008

Keywords

  • Attention
  • Emotion
  • Human

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Developmental Neuroscience
  • Developmental Biology
  • Behavioral Neuroscience

Fingerprint Dive into the research topics of 'Inhibitory deficits in Tourette's syndrome'. Together they form a unique fingerprint.

  • Cite this