Innovative Approaches to Hypertension Control in Low- and Middle-Income Countries

Rajesh Vedanthan, Antonio Bernabe-Ortiz, Omarys I. Herasme, Rohina Joshi, Patricio Lopez-Jaramillo, Amanda G. Thrift, Jacqui Webster, Ruth Webster, Karen Yeates, Joyce Gyamfi, Merina Ieremia, Claire Johnson, Jemima H. Kamano, Maria Lazo-Porras, Felix Limbani, Peter Liu, Tara McCready, J. Jaime Miranda, Sailesh Mohan, Olugbenga OgedegbeBrian Oldenburg, Bruce Ovbiagele, Mayowa Owolabi, David Peiris, Vilarmina Ponce-Lucero, Devarsetty Praveen, Arti Pillay, Jon David Schwalm, Sheldon W. Tobe, Kathy Trieu, Khalid Yusoff, Valentin Fuster

Research output: Contribution to journalReview articlepeer-review


Elevated blood pressure, a major risk factor for ischemic heart disease, heart failure, and stroke, is the leading global risk for mortality. Treatment and control rates are very low in low- and middle-income countries. There is an urgent need to address this problem. The Global Alliance for Chronic Diseases sponsored research projects focus on controlling hypertension, including community engagement, salt reduction, salt substitution, task redistribution, mHealth, and fixed-dose combination therapies. This paper reviews the rationale for each approach and summarizes the experience of some of the research teams. The studies demonstrate innovative and practical methods for improving hypertension control.

Original languageEnglish (US)
Pages (from-to)99-115
Number of pages17
JournalCardiology Clinics
Issue number1
StatePublished - Feb 1 2017


  • Community engagement
  • Hypertension
  • Low- and middle-income countries
  • Polypill
  • Salt reduction
  • Salt substitution
  • Task redistribution
  • mHealth

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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