Instrumentation for real-time dynamic optical tomography

Christoph H. Schmitz; Yaling Pei; Harry L. Graber; Joseph M. Lasker; Andreas H. Hielscher; Randall L. Barbour

doi:10.1117/12.447435

Instrumentation for real-time dynamic optical tomography

Christoph H. Schmitz, Yaling Pei, Harry L. Graber, Joseph M. Lasker, Andreas H. Hielscher, Randall L. Barbour

Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

An integrated system intended to serve as a general purpose optical imaging platform was described for the investigation of time-varying hemoglobin states and vascular reactivity in large tissue structures. The results of a time-series imaging study performed on a tumor-bearing and tumor-free breast of a subject diagnosed with a large ductal carcinoma was presented. Analysis of the time series provided evidence that unlike the coherent response of the tumor-free breast, the temporal dynamics of the tumor-bearing breast was largely incoherent.

Original language	English (US)
Title of host publication	SPIE-The International Society for Optical Engineering, Proc. 4431
Pages	282-291
Number of pages	10
DOIs	https://doi.org/10.1117/12.447435
State	Published - 2001

Keywords

Dynamic imaging
Instrumentation
Mammography
Optical tomography

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.447435

Cite this

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title = "Instrumentation for real-time dynamic optical tomography",

abstract = "An integrated system intended to serve as a general purpose optical imaging platform was described for the investigation of time-varying hemoglobin states and vascular reactivity in large tissue structures. The results of a time-series imaging study performed on a tumor-bearing and tumor-free breast of a subject diagnosed with a large ductal carcinoma was presented. Analysis of the time series provided evidence that unlike the coherent response of the tumor-free breast, the temporal dynamics of the tumor-bearing breast was largely incoherent.",

keywords = "Dynamic imaging, Instrumentation, Mammography, Optical tomography",

author = "Schmitz, {Christoph H.} and Yaling Pei and Graber, {Harry L.} and Lasker, {Joseph M.} and Hielscher, {Andreas H.} and Barbour, {Randall L.}",

year = "2001",

doi = "10.1117/12.447435",

language = "English (US)",

pages = "282--291",

booktitle = "SPIE-The International Society for Optical Engineering, Proc. 4431",

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T1 - Instrumentation for real-time dynamic optical tomography

AU - Schmitz, Christoph H.

AU - Pei, Yaling

AU - Graber, Harry L.

AU - Lasker, Joseph M.

AU - Hielscher, Andreas H.

AU - Barbour, Randall L.

PY - 2001

Y1 - 2001

N2 - An integrated system intended to serve as a general purpose optical imaging platform was described for the investigation of time-varying hemoglobin states and vascular reactivity in large tissue structures. The results of a time-series imaging study performed on a tumor-bearing and tumor-free breast of a subject diagnosed with a large ductal carcinoma was presented. Analysis of the time series provided evidence that unlike the coherent response of the tumor-free breast, the temporal dynamics of the tumor-bearing breast was largely incoherent.

AB - An integrated system intended to serve as a general purpose optical imaging platform was described for the investigation of time-varying hemoglobin states and vascular reactivity in large tissue structures. The results of a time-series imaging study performed on a tumor-bearing and tumor-free breast of a subject diagnosed with a large ductal carcinoma was presented. Analysis of the time series provided evidence that unlike the coherent response of the tumor-free breast, the temporal dynamics of the tumor-bearing breast was largely incoherent.

KW - Dynamic imaging

KW - Instrumentation

KW - Mammography

KW - Optical tomography

UR - http://www.scopus.com/inward/record.url?scp=0035759607&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035759607&partnerID=8YFLogxK

U2 - 10.1117/12.447435

DO - 10.1117/12.447435

M3 - Conference contribution

AN - SCOPUS:0035759607

SP - 282

EP - 291

BT - SPIE-The International Society for Optical Engineering, Proc. 4431

ER -

Instrumentation for real-time dynamic optical tomography

Abstract

Keywords

ASJC Scopus subject areas

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