Instrumentation for real-time dynamic optical tomography

Christoph H. Schmitz, Yaling Pei, Harry L. Graber, Joseph M. Lasker, Andreas H. Hielscher, Randall L. Barbour

    Research output: Contribution to journalArticlepeer-review


    An integrated system intended to serve as a general purpose optical imaging platform was described for the investigation of time-varying hemoglobin states and vascular reactivity in large tissue structures. The results of a time-series imaging study performed on a tumor-bearing and tumor-free breast of a subject diagnosed with a large ductal carcinoma was presented. Analysis of the time series provided evidence that unlike the coherent response of the tumor-free breast, the temporal dynamics of the tumor-bearing breast was largely incoherent.

    Original languageEnglish (US)
    Pages (from-to)282-291
    Number of pages10
    JournalProceedings of SPIE-The International Society for Optical Engineering
    StatePublished - 2001


    • Dynamic imaging
    • Instrumentation
    • Mammography
    • Optical tomography

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Condensed Matter Physics
    • Computer Science Applications
    • Applied Mathematics
    • Electrical and Electronic Engineering


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