Insulin-Like Growth Factor 1 Physiology. Lessons from Mouse Models.

Shoshana Yakar; Martin L. Adamo

doi:10.1016/j.ecl.2012.04.008

Insulin-Like Growth Factor 1 Physiology. Lessons from Mouse Models.

Shoshana Yakar, Martin L. Adamo

Molecular Pathobiology

Research output: Contribution to journal › Review article › peer-review

Abstract

Insulin-like growth factor 1 (IGF-1) is a pleiotropic polypeptide. Its expression is tightly regulated and it plays significant roles during early development, maturation, and adulthood. This article discusses the roles of IGF-1 in determination of body size, skeletal acquisition, muscle growth, carbohydrate metabolism, and longevity, as learned from mouse models.

Original language	English (US)
Pages (from-to)	231-247
Number of pages	17
Journal	Endocrinology and Metabolism Clinics of North America
Volume	41
Issue number	2
DOIs	https://doi.org/10.1016/j.ecl.2012.04.008
State	Published - Jun 2012

Keywords

IGF-1
Insulin-like growth factor 1
Mouse models
Physiology

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology

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10.1016/j.ecl.2012.04.008

Cite this

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abstract = "Insulin-like growth factor 1 (IGF-1) is a pleiotropic polypeptide. Its expression is tightly regulated and it plays significant roles during early development, maturation, and adulthood. This article discusses the roles of IGF-1 in determination of body size, skeletal acquisition, muscle growth, carbohydrate metabolism, and longevity, as learned from mouse models.",

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Insulin-Like Growth Factor 1 Physiology. Lessons from Mouse Models.

Abstract

Keywords

ASJC Scopus subject areas

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