INTEGRATE-AND-FIRE MODELS OF NERVE MEMBRANE RESPONSE TO OSCILLATORY INPUT.

J. P. Keener, F. C. Hoppensteadt, J. Rinzel

Research output: Contribution to journalArticlepeer-review

Abstract

Nerve membranes exhibit curious responses to alternating current stimulation, among which are phase locking, as well as reponses without apparent periodic pattern. These phenomena are investigated by presenting a complete analysis of the response to periodic input of an integrate-and-fire model, which is a simplified version of the Hodgkin-Huxley theory for space clamped nerves.

Original languageEnglish (US)
Pages (from-to)503-517
Number of pages15
JournalSIAM Journal on Applied Mathematics
Volume41
Issue number3
DOIs
StatePublished - 1981

ASJC Scopus subject areas

  • Applied Mathematics

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